NEW YORK, N.Y. – British playwright Lucy Prebble’s “The Effect,” about the relationship between science and love, will make its North American debut this spring at the Barrow Street Theatre.

David Cromer will direct the work, which won the 2012 UK Critics’ Circle Award for Best New Play. Cromer recently directed celebrated productions of “Tribes” and “Our Town” at the Barrow Street Theatre.

The new play, produced by The National Theatre of Great Britain, will open in March and will mark the first time the theatrical powerhouse has ventured off-Broadway. It is also being produced in collaboration with Jean Doumanian Productions and Barrow Street Theatre.

“The Effect” follows two young people who become romantic during a clinical trial for a new anti-depressant. They can’t be sure if their relationship is true or they’re just enjoying elevated dopamine levels.

Prebble wrote the plays “The Sugar Syndrome and “Enron,” as well as the television series “Secret Diary of a Call Girl.” She is currently developing a scripted comedic TV series with comedienne Sarah Silverman for HBO.

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Online: http://www.barrowstreettheatre.com

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Follow Mark Kennedy at http://twitter.com/KennedyTwits . His work can be found at http://bigstory.ap.org/content/mark-kennedy