Some of the most active companies traded Wednesday on the Toronto Stock Exchange:

Toronto Stock Exchange (14,626.24, down 138.53 points):

Telesta Therapeutics Inc. (TSX:TST). Health care. Up 6.5 cents, or 92.86 per cent, to 13.5 cents on 49.5-million shares.

Acerus Pharmaceuticals Corp. (TSX:ASP). Drug manufacturers. Up 4.5 cents, or 25 per cent, to 22.5 cents on 8.4-million shares.

B2Gold Corp. (TSX:BTO). Miner. Down 30 cents, or 7.58 per cent, to $3.66 on seven-million shares.

First Quantum Minerals Ltd. (TSX:FM). Miner. Down 97 cents, or 8.05 per cent, to $11.08 on 6.7-million shares.

Baytex Energy Corp. (TSX:BTE). Oil and gas. Down 36 cents, or 5.27 per cent, to $6.47 on 6.1-million shares.

Yamana Gold Inc. (TSX:YRI). Miner. Down 66 cents, or 10.23 per cent, to $5.79 on 5.8-million shares.

Companies reporting major news:

AlarmForce Industries Inc. (TSX:AF). Security systems. Down 80 cents, or 7.08 per cent, to $10.50 on 83,789 shares. AlarmForce says some of its customers were incorrectly billed over a three-year period, resulting in a delay of its next financial report. The Toronto-based company said in a statement it shouldn’t have continued charging monitoring fees to customers in some jurisdictions after they cancelled their subscriptions but before they returned AlarmForce’s equipment.

Royal Bank of Canada (TSX:RY). Bank. Down 37 cents, or 0.45 per cent, to $81.86 on 2.7-million shares. Royal Bank had $2.895 billion of net income in its third quarter, up 17 per cent from a year ago — in part because of the sale of an insurance business. The bank had a profit of $2.475 billion during the same quarter last year. The earnings amounted to $1.88 per share, up from $1.66 during the same quarter in 2015.