Most actively traded companies on the TSX

Some of the most active companies traded Tuesday on the Toronto Stock Exchange:

Toronto Stock Exchange (13,304.66, down 31.49 points):

Telesta Therapeutics Inc. (TSX:TST). Health-care. Up three cents, or 35.29 per cent, to 11.5 cents on 28.4 million shares.

Pacific Exploration & Production Corp. (TSX:PRE). Oil and gas. Down six cents, or 6.06 per cent, to 93 cents on 10.2 million shares.

Lake Shore Gold Corp. (TSX:LSG). Miner. Up 12 cents, or 6.42 per cent, to $1.99 on 8.4 million shares.

B2Gold Corp. (TSX:BTO). Miner. Up three cents, or 1.42 per cent, to $2.15 on seven million shares.

Bombardier Inc. (TSX:BBD.B). Aerospace, rail equipment. Down one cent, or 0.78 per cent, to $1.27 on 6.8 million shares.

Semafo Inc. (TSX:SMF). Miner. Down 35 cents, or 7.43 per cent, to $4.36 on 6.1 million shares.

Companies reporting major news:

Valeant Pharmaceuticals International Inc. (TSX:VRX). Drugs, health-care products. Up $3.44, or 10.02 per cent, to $37.77 on two million shares. Faced with underwhelming sales, the company plans to relaunch its Addyi female sexual dysfunction drug and to replace 140 contract sales representatives for the product. Valeant acquired Addyi when it bought Sprout Pharmaceuticals last year for US$1 billion cash, plus a share of future profits.